• Repurpose or Innovate: Sustained release changes everything

    TheraKine is partnering with global biopharmaceutical companies

  • Take control  with sustained release injectable formulations

    TheraKine is partnering with global biopharmaceutical companies

  • Life cycle management with significant performance advantages

    TheraKine is partnering with global biopharmaceutical companies

  • Organ-specific formulations? We do that!

    TheraKine is partnering with global biopharmaceutical companies

  • Local sustained delivery for your drug

    TheraKine is partnering with global biopharmaceutical companies

  • Become BIOBETTER with TheraKine

    TheraKine is partnering with global biopharmaceutical companies

TheraKine Limited is a privately held drug delivery Company

Partnering

TheraKine has partnerships with global biopharmaceutical companies in a variety of therapeutic areas. The disclosable partnerships, such as our JV with RBCC, are disclosed on the Press Page.


What can we do for your drug programs?

Formulation packages are offered for your pharmaceutical products at any stage in their life cycle. We offer an in-depth discussion of your drug delivery objective in advance of any work to ensure that objectives are clearly understood. There are some drugs or indications for which our tunable sutained release technologies may not be helpful. We want to make sure that our efforts align to your goals.

Feasibility: 4 to 6 weeks

To start work we will need to establish, under CDA, your requirements and the properties of the drug to be formulated using our technology.

Multiple formulations with different payloads and GRAS materials will be evaluated to create matrices which demonstrate release properties similar to those you request, and the release kinetics will be measured in-vitro in TheraKine's laboratory. third-party testing is available if you desire external verification. We will provide you with results and our assessment of the suitability of the matrices for further development.

Formulation Refinement: 2 to 6 months in most cases

The chosen feasibility formulations and variations will be created and tested to refine performance with respect to the dose, release profile, and other desired properties. The system will be adapted to your application conditions (hydrophilic or hydrophobic, injectable, paste, microparticle suspension, implant).

Samples can be provided for your own evaluation and testing.

The duration of this stage depends on the chosen formulations, since real-time verification of release kinetics is included in our analysis. For example, a three-month release profile requires three months after formulation to complete verification of the kinetics in-vitro.

Formulation Finalization:

Finalization of the formulation to achieve all required properties, application compatibility, and creation of a complete formulation method dossier, along with samples needed for in-vitro and in-vivo testing.